湖北科技学院学报（医学版）

目的 调查老年女性心血管病高危人群危险因素对健康相关生命质量的影响。方法 采用多阶段分层整群抽样方法，调查60～75岁女性4667人。使用多因素二分类logistic回归分析老年女性心血管病高危人群危险因素；采用Tobit回归模型分析EQ-5D健康效用值的影响因素。结果 老年女性心血管病高危人群危险因素为：年龄(OR:1.367,95%CI:1.158～1.614)、超重及肥胖(OR:1.444,95%CI:1.264～1.650)、打鼾(OR:1.249,95%CI:1.094～1.426)。EQ-5D健康效用均值得分为(0.987±0.053),行动能力、自理能力、日常生活能力和疼痛或不舒服报告有困难率分别为2.1%、0.3%、0.8%、5.5%。Tobit回归结果显示，收入(Tobit回归系数：-1.358,95%CI:-2.211～-0.505)和脑卒中病史(Tobit回归系数：-0.644,95%CI:-1.180～-0.108)是健康效用值的影响因素，家庭年收入高于5万者以及有脑卒中病史者，其生命质量更低。结论 为预防控制老年女性心血管疾病，应重点干预超重或肥胖以及打鼾人群；加强对有脑卒中病史老年女性的随访，以提高其生命质量。

Objective To investigate the impact of risk factors on health-related quality of life in elderly women at high risk of cardiovascular disease.MethodsA total of 4667 women aged 60 to 75 were surveyed by multi-stage stratified cluster sampling method.Multivariate binary logistic regression was used to analyze the risk factors of elderly women with high risk of cardiovascular disease.Tobit regression model was used to analyze the influencing factors of EQ-5D health utility value.Results Risk factors for elderly women with high risk of cardiovascular disease included age(OR:1.367,95%CI:1.158～1.614),overweight and obesity(OR:1.444,95%CI:1.264～1.650),snoring(OR:1.249,95%CI:1.094～1.426).The average score of EQ-5D health effect value was 0.987±0.053,and the rates of mobility ability, self-care ability, daily living ability, and difficulty reporting pain or discomfort were 2.1%,0.3%,0.8%,5.5%,respectively.Tobit regression results showed that income and stroke history were the influencing factors of health utility value, and those with annual household income over 50,000 and stroke history had lower quality of life.Conclusion In order to prevent and control cardiovascular disease in elderly women, interventions should be focused on overweight or obese and snoring groups.Follow-up of elderly women with a history of stroke should be strengthened to improve their quality of life.